Ischemia-preconditioning induced serum exosomal miR-133a-3p improved post-myocardial infarction repair via targeting LTBP1/TGF-β1/PPP2CA axis

ABSTRACT: This study found that IPC-induced serum exosomes inhibit myocardial fibrosis and improve cardiac function following MI by transferring miR-133a-3p, which targets LTBP1 and PPP2CA, to regulate the TGF-β signaling pathway in rats.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE272122 | GEO | 2024/09/18

REPOSITORIES: GEO