Characteriration of mitochondrial stress response in Luhmes-derived dopaminergic neurons; Comparative expression profile using RNAseq after 8 hours of Antimycin + Oligomycin treatment in differentiated Luhmes cells

ABSTRACT: Responsiveness of 6 days old differentiated Luhmes cells to mitochondrial stress induced by 8 hours treatment with Antimycin-A and Oligomycin analyzed by RNA-seq. The Unfolded Protein Response of the Endoplasmic Reticulum is induced upon stress in human dopaminergic neurons, and modulates mitochondrial homeostasis and transcriptional programs including expression of long non-coding RNAs (lncRNAs).

ORGANISM(S): Homo sapiens

PROVIDER: GSE272241 | GEO | 2026/07/31

REPOSITORIES: GEO