Lipid engulfed macrophages interfere with protective T cell immunity and favor tumor progression in human colon carcinogenesis - Monocyte

ABSTRACT: Obesity and altered lipid metabolism are associated with colorectal cancer (CRC). In this context, the presence of colonic lipid-engulfed macrophages (foam cells, FC) may hinder protective T cell immunity, thus favoring gut carcinogenesis.

ORGANISM(S): Homo sapiens

PROVIDER: GSE273106 | GEO | 2024/07/25

REPOSITORIES: GEO