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Mouse Wild Type Tissue Survey

ABSTRACT: Survey of gene expression in 9 types of C57/Bl mouse wild type tissue.

ORGANISM(S): Mus musculus Homo sapiens

PROVIDER: GSE27346 | GEO | 2011/02/17

SECONDARY ACCESSION(S): PRJNA137411

REPOSITORIES: GEO

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Mouse Wild Type Tissue Survey

Project description:Survey of gene expression in 9 types of C57/Bl mouse wild type tissue. RNA was extracted from homogenized whole organs/tissues and include brain, spleen, liver, thymus, kidney, lung, testes, bone marrow, and lymph node. 8 week old male littermate C57/Bl mice

2011-02-17 | E-GEOD-27346 | biostudies-arrayexpress

Identification of Bmal1 binding sites by ChIP-seq in mouse lung tissue

Project description:Bmal1 ChIP-seq on C57/BL adult mouse lung tissue at Zeitgeber time ZT5.

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Campylobacter jejuni murine adaptation: unadapted v. adapted during growth in C57 BL/6 IL-10-/- germ-free mice.

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RNA Sequencing of Wild Type and CCR2-/- mouse esophageal tumor transcriptomes

Project description:Wild type and CCR2-/- C57 mice were gavaged with carboxyl methyl cellulose (1%) or N-nitrosomethylbenzylamine(NMBA) 0.25 mg/kg body weight (BW) twice per week for 5 weeks. At the end of Week 25, the forestomach were harvested to carry out RNA resequencing. We found that CCR2 mediated monocyte infiltration promoted tumor evasion through activating PD-1 signaling pahtway.

2019-09-10 | GSE134067 | GEO

sRNA sequencing from wild-type Arabidopsis (diverse tissue types)

Project description:This set consists of small RNAs sequenced from wild-type Arabidopsis samples from multiple tissue types (floral, leaf, seedling, silique). Samples were prepared in two different labs and presumably under different (unknown) growth conditions, hence type A (UEA) and type B (University of Cambridge) samples.

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MicroRNA profiling of mouse wild type (C57 and 129) retina and retina from a mouse model of retinitis pigmentoas (Pro347Ser)

Project description:Experiment to examine the miRNA profiles of a wild type C57 and 129 mouse retina versus a retina from a mouse model of retinitis pigmentoas (Pro347Ser)

2007-11-22 | E-TABM-329 | biostudies-arrayexpress

Campylobacter jejuni murine adaptation: unadapted v. adapted during growth in C57 BL/6 IL-10-/- germ-free mice.

Project description:Expression arrays comparing Campylobacter jejuni 11168 before and after serial passage in C57 BL/6 IL-10 deficient mice. Transcript abundance was compared between C. jejuni variants during growth in the ceca of C57 BL/6 IL-10 deficient germ-free mice. Unpassaged (p0) C. jejuni 11168 was compared to the same strain after three passages (p3) through the mice. Biological replicates: 4; 2 biological replicates were dye swaps.

2010-08-27 | E-GEOD-23811 | biostudies-arrayexpress

Cell-Type-Specific Survey of Epigenetic Modification by Tandem Chromatin Immunoprecipitation Sequencing

Project description:[Background]: Nervous system of higher eukaryotes is composed of numerous types of neurons and glia, which together orchestrate complex neuronal responses. However, the complex pool of cells usually poses analytic challenges to investigate gene expression profile and its epigenetic basis in specific cell type. Here we developed a novel method that enables cell-type-specific analyses of epigenetic modification using tandem chromatin immunoprecipitation sequencing (tChIP-Seq). [Results]: FLAG-tagged histone H2B, a constitutive chromatin component, was firstly expressed in Camk2a-positive pyramidal cortical neurons and was used to purify the chromatin in a cell-type-specific manner. The subsequent chromatin immunoprecipitation using antibodies against H3K4me3—an active promoter mark—allowed us to survey neuron specific coding and noncoding transcripts. Indeed, tChIP-Seq identified hundreds of genes associated with neuronal functions as well as genes with unknown function expressed in cortical neurons. [Conclusions]: tChIP-Seq thus provides a versatile approach to investigate epigenetic modifications of particular cell types in vivo.

2018-01-08 | GSE100628 | GEO

MicroRNA profiling of mouse wild type (C57) retina and a retina from a mouse model of retinitis pigmentosa (Pro347Ser)

Project description:Experiment to examine the miRNA profiles in the retina compared to the brain and other body regions. A comparison of a wild type C57 mouse retina versus a retina from a mouse model of retinitis pigmentosa (Pro347Ser) was under taken.

2007-11-22 | E-TABM-332 | biostudies-arrayexpress

Campylobacter jejuni murine adaptation: unadapted v. adapted

Project description:Expression arrays comparing Campylobacter jejuni 11168 before and after serial passage in C57 BL/6 IL-10 deficient mice. Gene expression was compared during exponential growth in Bolton broth.

2009-08-08 | GSE17562 | GEO

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