Transcriptomics

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Gene expression profile at single cell level of islets from two β-cell specific knockout mouse models (βZKO-Mip and βZKO-Rip), littermate controls (Zzef1f/f), and the MIP-Cre mice fed with normal-chow diet (NCD).


ABSTRACT: Islet consists of multiple cell types that work in concert to orchestrate their endocrine function. To rule out of direct effect of diet or phenotype, we performed comparative single-cell RNA-sequencing (scRNA-seq) on 12-week βZKO-Mip, βZKO-Rip mice, littermate controls (Zzef1f/f) and MIP-Cre mice islets fed with normal-chow diet (NCD) by Chromium Next GEM Single Cell 3’ Reagent Kits.

ORGANISM(S): Mus musculus

PROVIDER: GSE273688 | GEO | 2025/09/22

REPOSITORIES: GEO

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