Whole transcriptome analysis reveals T cell signaling activation in septic patients with thrombocytopenia

ABSTRACT: Sepsis, a life-threatening condition triggered by a dysregulated immune response to infection, remains one of the leading causes of mortality worldwide. Thrombocytopenia, a common sepsis complication, is linked to poor outcomes and reflects disease severity and specific immunological changes affecting patient outcomes. This study aims to elucidate this relationship using whole-transcriptome RNA sequencing (RNA-Seq) in intensive care unit (ICU) patients with sepsis.

ORGANISM(S): Homo sapiens

PROVIDER: GSE273700 | GEO | 2026/01/28

REPOSITORIES: GEO