Cardiomyocyte development from human induced pluripotent stem cells (iPSC)

ABSTRACT: Induced-pluripotent stem cell-derived cardiomyocyte (IPSC-CM) models can improve understanding of pathophysiology through disease modelling and can be used for cardiotoxicity screening of drugs, ultimately reducing reliance on animal models; however these models have not been extensively functionally characterised, which was the aim of this study. A contracting IPSC-CM model was generated and characterised for atrial and ventricle-specific cardiac gene expression with RNAsequencing. These data are to be correlated with functional assays.

ORGANISM(S): Homo sapiens

PROVIDER: GSE273793 | GEO | 2025/09/01

REPOSITORIES: GEO