Single-cell transcriptomic analysis of midbrain organoids of bipolar disorder patients reveals a mechanism of lithium response

ABSTRACT: Bipolar disorder (BD) is a complex neuropsychiatric disorder involving pathophysiological changes in multiple brain regions, which, however, remain poorly understood.We generated human midbrain organoids (hMOs) to investigate the midbrain pathophysiology of BD.

ORGANISM(S): Homo sapiens

PROVIDER: GSE273922 | GEO | 2026/08/11

REPOSITORIES: GEO