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Single-cell resolution spatial analysis of antigen-presenting cancer-associated fibroblast niches [scRNA-seq]

ABSTRACT: To understand the microenvironmental changes caused by Spp1 knockout, we digested the tumors from the control and knockout groups into single cell suspension and performed scRNA-seq. The scRNA-seq data suggested a significant increase of T cell infiltration into the stromal Spp1 knockout tumors.

ORGANISM(S): Mus musculus

PROVIDER: GSE274609 | GEO | 2025/09/15

REPOSITORIES: GEO

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