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Effect of BMP signaling levels on foregut specification during directed differentiation of BU3 NGPT human induced pluripotent stem cells

ABSTRACT: To investigate the dose dependent effects of BMP signaling on foregut organ domain specification, we treated hiPSC derived definitive endoderm with 0μM, 1μM or 2μM of BMP inhibitor DSM during days 3-6 of directed differentiation. We then preformed gene expression analysis of D6 samples between the 3 treatment groups using data generated from the RNA seq

ORGANISM(S): Homo sapiens

PROVIDER: GSE274939 | GEO | 2025/08/15

REPOSITORIES: GEO

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