Isolation and characterization of a metastatic hybrid cell line generated by ER negative and ER positive breast cancer cells in mouse bone marrow

ABSTRACT: The origin and the contribution of breast tumor heterogeneity to its progression are not clear. We investigated the effect of a growing orthotopic tumor formed by an aggressive estrogen receptor (ER)-negative breast cancer cell line on the metastatic potential of a less aggressive ER-positive breast cancer cell line for the elucidation of how the presence of heterogeneous cancer cells might affect each other’s metastatic behavior.

ORGANISM(S): Homo sapiens

PROVIDER: GSE27515 | GEO | 2011/05/25

SECONDARY ACCESSION(S): PRJNA138583

REPOSITORIES: GEO