Characterization of E2F8-mediated transcriptional regulation in lethal prostate cancer

ABSTRACT: To identify the genomic bindings and transcriptional targets of E2F8 in lethal prostate cancer cells. To examine the potential off-target effects by CRISPR/CasRx-mediated E2F8 knockdown in 293FT cells. To analyze differentially expressed genes upon TT3 LLN-CRISPR/CasRx-mediated E2F8 knockdown in DU145 xenografts.

ORGANISM(S): Homo sapiens

PROVIDER: GSE275631 | GEO | 2025/01/10

REPOSITORIES: GEO