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ScRNA-seq and TCR-seq of T cells and APCs in tumor-draining lymph nodes with versus without pharmacological LXR activation.

ABSTRACT: Here we assessed the impact on the transcriptomes of T cells and APCs in tumor-draining lymph nodes from mice administered control chow versus chow containing the synthetic LXR agonist RGX-104. In addition, TCR-seq was performed to assess the impact on clonal expansion of T cells upon LXR activation.

ORGANISM(S): Mus musculus

PROVIDER: GSE275714 | GEO | 2025/12/31

REPOSITORIES: GEO

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