Transcriptomics

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Differential gene expression in the knee of DBA/1 mice with spontaneous arthritis (SpAD) compared to healthy BALB/c mice


ABSTRACT: The DBA/1 mouse strain produces spontaneous arthritis (SpAD) characterized by an inflammatory process and changes in the joint structures that resemble human spondyloarthritis. Normally, it is the hind paws that are analyzed in this model and information on the alterations in the knee is very scarce. Transcriptome analysis was performed using DNA microarrays of knees of DBA/1 strain mice with spontaneous arthritis (SpAD) and BALB/c strain mice as a control.

ORGANISM(S): Mus musculus

PROVIDER: GSE276030 | GEO | 2025/08/31

REPOSITORIES: GEO

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