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Single cell spatial transcriptome and RNA-seq analysis in human lung tissues with mycobacterial infection: Single cell spatial transcriptome


ABSTRACT: Tuberculosis and non-tuberculous mycobacterial (NTM) diseases are infections caused by Mycobacterium tuberculosis and non-tuberculous mycobacteria, leading to the formation of granulomatous lesions with caseous necrosis in the lungs. We applied spatial transcriptomics at single-cell resolution (CosMx Spatial Molecular Imaging) to human lung samples from patients with mycobacterial infections. RNA-seq was also performed on the samples.

ORGANISM(S): Mus musculus Homo sapiens

PROVIDER: GSE276083 | GEO | 2025/08/29

REPOSITORIES: GEO

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