Performing RNA sequencing on wild-type and Arrb2 knockout mouse primary astrocytes within the MPP+ model

ABSTRACT: We aimed to investigate the potential mechanism underlying the phenotypic transformation of astrocytes mediated by β-arrestin2. Primary astrocytes were isolated and cultured from the midbrain of neonatal WT and Arrb2 KO mice. RNA sequencing (RNA-Seq) was performed to compare the transcriptome of astrocytes in the context of MPP+ treatment.

ORGANISM(S): Mus musculus

PROVIDER: GSE276420 | GEO | 2025/09/05

REPOSITORIES: GEO