Transcriptomic signatures of antibody mediated rejection in early biopsies with negative histology in HLA incompatible kidney transplantation [RNA-seq]

ABSTRACT: Presensitized patients with circulating donor-specific antibodies (DSA) prior to transplantation are at risk for antibody-mediated rejection (ABMR). Peritransplant desensitization mitigates but does not eliminate the alloimmune response. We examined the possibility that subthreshold ABMR activity undetected by histology could be operating in some early biopsies.

ORGANISM(S): Homo sapiens

PROVIDER: GSE276593 | GEO | 2024/12/26

REPOSITORIES: GEO