Transcriptomics

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Hypoxia Induces Endothelial Cell Transition into Circulating Endothelial Cells in Post-Transplant Thrombotic Microangiopathy.


ABSTRACT: We report a case of post-transplant thrombotic microangiopathy (PT-TMA) in a kidney transplant patient. Combining renal biopsy with single-cell sequencing revealed significant endothelial damage and elevated circulating endothelial cells (CECs). Hypoxia pathways played a critical role in CEC formation, providing new insights into PT-TMA pathogenesis.

ORGANISM(S): Homo sapiens

PROVIDER: GSE276822 | GEO | 2025/07/02

REPOSITORIES: GEO

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