An IL-33–LMO4 axis instructs type 2 myelopoiesis via GATA factor re-allocation (G320D RNA-Seq)

ABSTRACT: In this study we examine the role of LMO4 and it regulation by helminth infection in type 2 myelopoiesis. The effect of LMO4 on type 2 myeloid progenitors is examined by RNAseq and ATACseq, as well as functional readouts, to establish the mechanism by which LMO4 carries out its lineage instructive effect.

ORGANISM(S): Mus musculus

PROVIDER: GSE276826 | GEO | 2026/02/01

REPOSITORIES: GEO