Transcriptomics

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Impact of LINE-1 overexpression on gene expression in human induced pluripotent stem cell-derived microglia


ABSTRACT: The aberrant expression of the transposable element LINE-1 is posited to impact cellular function and contribute to disease. We report that LINE-1 overexpression in these microglial cells drives significant functional and transcriptomic changes, including altered expression of genes associated with antigen presentation.

ORGANISM(S): Homo sapiens

PROVIDER: GSE276905 | GEO | 2024/12/06

REPOSITORIES: GEO

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