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Comprehensive Transcriptomic and Translational Profiling of Human Embryonic Stem Cell Differentiation to Definitive Endoderm and Pancreatic Progenitors via RNA-seq and Ribo-seq

ABSTRACT: This study presents a detailed transcriptomic and translational analysis of human embryonic stem cells (hESCs) as they differentiate into definitive endoderm (DE) and pancreatic progenitor stages (PP1 and PP2). We employed RNA sequencing (RNA-seq) to capture the transcriptional landscape and ribosome profiling (Ribo-seq) to assess translational regulation throughout the differentiation process.

ORGANISM(S): Homo sapiens

PROVIDER: GSE277202 | GEO | 2025/04/19

REPOSITORIES: GEO

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