CSF1R marks a subset of foetal LMPPs with Acute Myeloid Leukaemia propagation properties in a KMT2A-MLLT3 mouse model

ABSTRACT: As KMT2A-MLLT3 oncoprotein can give rise to ALL and AML in infants, we investigated whether such choice could lie in two subsets of foetal LMPPs, that express or not CSF1R, and found that CSF1R mark a more potent subpopulation with leukaemic-initiating

ORGANISM(S): Mus musculus

PROVIDER: GSE277342 | GEO | 2025/11/25

REPOSITORIES: GEO