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Effect of p.E475G mutation in the PNPT1 gene on 293T global transcriptome

ABSTRACT: We genereted via genome editing 293T cell lines with the heterozygous and homozygous nucleotide substitution c.1424A>G in the PNPT1 gene (namely EK81 and EK81.8, respectively), causing the amino acidic variation p.E475G, and studied their transcriptomes before and after 6 hours of treatment with 1 µM staurosporine to induce apoptosis

ORGANISM(S): Homo sapiens

PROVIDER: GSE277568 | GEO | 2024/10/07

REPOSITORIES: GEO

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