Time course analysis of gene expression in the liver of a 70% partial hepatectomy mouse model.

ABSTRACT: The liver has a remarkable regenerative capacity, allowing it to regain mass through compensatory hypertrophy of the remaining tissue after the surgical removal of 70% of its mass. During this regenerative process, lipid accumulation and proliferation of liver parenchymal cells have been observed; however, the full extent of the underlying regenerative mechanisms remains unclear. Our study performed a comprehensive gene expression analysis using microarrays on liver samples collected at 0, 0.25, 0.5, 0.75, 1, 1.5, 2, 3, 4, 7, and 14 days following 70% partial hepatectomy in mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE278618 | GEO | 2025/04/22

REPOSITORIES: GEO