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Transcriptomic profiling of MDA-MB-453 breast cancer cells following ZNF207 overexpression

ABSTRACT: This RNA-sequencing study was designed to characterize transcriptional changes associated with ZNF207 overexpression in MDA-MB-453 breast cancer cells and to identify downstream pathways. MDA-MB-453 cells transfected with a control vector or a ZNF207-overexpression construct were analyzed, with three independent biological replicates per group. Differential expression and pathway enrichment analyses were performed to compare ZNF207-overexpressing cells with control cells. The dataset itself does not contain drug-treated samples. Findings from separate functional assays in the associated manuscript indicate that ZNF207 is linked to breast cancer progression and chemotherapy response.

ORGANISM(S): Homo sapiens

PROVIDER: GSE279294 | GEO | 2024/10/16

REPOSITORIES: GEO

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