Bifidobacterium lactis Derived Vesicles Attenuates Hippocampal Neuroinflammation via Targeting IL-33 to Regulate FoxO6/P53 Signaling

ABSTRACT: Hippocampal Neuroinflammation (HNF) is a critical driver of cognitive impairment. The lipo-polysaccharide (LPS) accumulate amyloid beta (Aβ) and lead to HNF. The Bifidobacterium lactis (BL) 99 have anti-inflammatory ability. However, the whether BL99-derived microbiota-derived vesi-cles (MV) could alleviate LPS induced HNF remain unclear.

ORGANISM(S): Mus musculus

PROVIDER: GSE279453 | GEO | 2025/10/01

REPOSITORIES: GEO