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Gene expression profiling of CD11c+ or CD11b+ cells from bronchoalveolar lavage fluid was conducted in a bleomycin-induced pulmonary fibrosis model following GW5074 treatment or in Clec7a KO mice

ABSTRACT: To investigate the role of the Dectin-1 signaling pathway in the development of pulmonary fibrosis, we established a BLM-induced pulmonary fibrosis model using WT mice, Dectin-1-deficient mice (Clec7a–/–, KO), and GW5074-treated mice. CD11b+ or CD11c+ cells were sorted by flow cytometry and subjected to single-cell RNA sequencing.

ORGANISM(S): Mus musculus

PROVIDER: GSE279528 | GEO | 2025/07/01

REPOSITORIES: GEO

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