Transcriptomics

Dataset Information

0

Expression data from CH/LE Mice


ABSTRACT: We are using genome-wide ChIP-seq with isoform-specific antibodies and chromatin from select tissues of mice challenged with different dietary conditions that enrich for specific SREBPs. We show that hepatic SREBP-2 binds preferentially to two different gene-proximal motifs as well as SREBP-2 directly activates autophagy genes during cell sterol depletion, conditions known to induce both autophagy and nuclear SREBP-2 levels.

ORGANISM(S): Mus musculus

PROVIDER: GSE28083 | GEO | 2011/03/23

SECONDARY ACCESSION(S): PRJNA143127

REPOSITORIES: GEO

Similar Datasets

2011-03-22 | E-GEOD-28083 | biostudies-arrayexpress
2011-03-22 | E-GEOD-28082 | biostudies-arrayexpress
2011-03-23 | GSE28082 | GEO
2017-08-05 | GSE102257 | GEO
2017-08-05 | GSE102256 | GEO
2017-08-05 | GSE102258 | GEO
2011-01-08 | E-GEOD-26496 | biostudies-arrayexpress
2011-01-08 | GSE26496 | GEO
2017-04-11 | GSE95807 | GEO
2022-04-05 | GSE174173 | GEO