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Assessing the contribution of RIPK1 in ZIKV-induced inflammatory transcription in neuorns

ABSTRACT: We previously have found that RIPK3 induces robust anti-viral and inflammatory transcriptional signaling in primary cortical neurons, however the complete molecular mechanism governing this pathway is incompletely understood. Here we show RIPK1 is required to induce RIPK3-dependent transcription in ZIKV-infected neurons.

ORGANISM(S): Mus musculus

PROVIDER: GSE281172 | GEO | 2025/05/07

REPOSITORIES: GEO

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