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Discovery of Gene Expression Signature in the Overexpression of miR-145 in U87 glioma cell.

ABSTRACT: We have employed whole RNA microarray expression profiling as a discovery platform to identify genes regulated by overexpression of miR-145 in U87 glioma cell. Lentivirus containing miR-145 coding sequence was infected to U87 cell to make U87 overexpressing miR-145. We did genome microarray between U87 and U87 overexpressing miR-145.

ORGANISM(S): Homo sapiens

PROVIDER: GSE28121 | GEO | 2011/03/25

SECONDARY ACCESSION(S): PRJNA139841

REPOSITORIES: GEO

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Discovery of Gene Expression Signature in the Overexpression of miR-145 in U87 glioma cell.

Project description:We have employed whole RNA microarray expression profiling as a discovery platform to identify genes regulated by overexpression of miR-145 in U87 glioma cell. Lentivirus containing miR-145 coding sequence was infected to U87 cell to make U87 overexpressing miR-145. We did genome microarray between U87 and U87 overexpressing miR-145. Total RNAs from U87 cell or U87 overexpressing miR-145 were extracted. Whole RNA microarray expression profiling was performed between them.

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