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In situ single-cell profiling of lung metastases from the MMTV-PyMT mouse model of metastatic breast cancer

ABSTRACT: A key problem in cancer biology is understanding the phenotypic characteristics of the aggressive cell states present in macrometastases and their molecular underpinnings. Here we report on the cellular constituents of breast cancer metastases, revealing that these malignant cells display a gene-expression profile associated to embryonic development of tubular organs.

ORGANISM(S): Mus musculus

PROVIDER: GSE281489 | GEO | 2026/03/27

REPOSITORIES: GEO

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