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Transcriptional profiling of aged and young mouse hearts [scMulti-ome]

ABSTRACT: Cardiac aging is a major risk factor for cardiovascular diseases, yet the underlying molecular mechanisms remain poorly understood. In this study, we employed a multi-omics approach combining single-nucleus RNA-seq, ATAC-seq, and reduced representation bisulfite sequencing (RRBS) to comprehensively characterize the cellular and molecular landscape of cardiomyocyte (CM) aging in mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE281772 | GEO | 2025/11/11

REPOSITORIES: GEO

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Transcriptional profiling of aged and young mouse hearts [RRBS]

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