Transcriptional regulation by the stringent response-associated alarmone (p)ppGpp in Pseudomonas putida

ABSTRACT: The stringent response is an adaptive physiological response triggered by different conditions of nutritional or environmental stress and aimed at increasing survival under harsh conditions. This response is mediated the signalling nucleotides guanosine tetraphosphate (ppGpp) and pentaphospate (pppGpp), collectively known as (p)ppGpp. In this study we aim to identify genome-wide targets of regulation by the stringent-response associated alarmone (p)ppGpp in Pseudomonas putida by performing RNA-seq experiments using the wild-type KT2440tel strain and a KT2440tel-derivative bearing deletions of the (p)ppGpp synthetase-encoding genes relA and spoT (ppGpp0 mutant).

ORGANISM(S): Pseudomonas putida

PROVIDER: GSE281821 | GEO | 2024/11/18

REPOSITORIES: GEO