Genetically encoded fluorescent reporters to visualize Lewy pathology in live brain

ABSTRACT: Lewy bodies, a pathological hallmark of Parkinson’s disease, are α-synuclein-enriched cytoplasmic inclusions that drive progressive neurodegeneration these reporters provide an opportunity to directly visualize α-synuclein inclusions in live brains and support various applications for measuring their pathological effects on individual neurons.

ORGANISM(S): Mus musculus

PROVIDER: GSE282108 | GEO | 2026/01/17

REPOSITORIES: GEO