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Expression data from OP- and OC- treated primary normal human epidermal keratinocytes (HEK).

ABSTRACT: Oleuropein (OP) and Oleacein (OC) are enriched components in Olive (oil and leaves). However, their effects on skin have not been widely studied. Here, we perfomed global gene expression profiling to screen the potential effects of OP and OC on the skin. Results showed that OP and OC effectively regulated the key markers of differentiation. It suggested that olive-derived secoiriodids have the potential to support the skin barrier formation. HEK cells were treated with 10ng/ml KGF, 200nM of OP and OC, respectively, for 96 hours under high calcium conditions to induce the differentiation. Microarray gene expression profiling was conducted biological triplicates.

ORGANISM(S): Homo sapiens

PROVIDER: GSE282485 | GEO | 2025/11/22

REPOSITORIES: GEO

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