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Expression profiles osteosarcoma cell lines and MET transformed osteoblast clones

ABSTRACT: We studied MET-transformed human primary osteoblasts (MET-HOBs), which we previously turned into osteosarcoma cells by LV driven over-expression of MET oncogene. We obtained distinct MET transformed HOB clones derived from independent events of transgene integration. To characterise the phenotype of the MET-HOB clones we used oligonucleotide microarrays. Expression profiles of MET-HOBs and osteosarcoma cell lines were compared.

ORGANISM(S): Homo sapiens

PROVIDER: GSE28252 | GEO | 2013/02/28

SECONDARY ACCESSION(S): PRJNA139799

REPOSITORIES: GEO

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Expression profiles of human primary osteoblasts (HOB) and MET transformed osteoblast clones

Project description:We studied MET-transformed human primary osteoblasts (MET-HOBs), which we previously turned into osteosarcoma cells by LV driven over-expression of MET oncogene. We obtained distinct MET transformed HOB clones derived from independent events of transgene integration. To characterise the phenotype of the MET-HOB clones we used oligonucleotide microarrays. Expression profiles of MET-HOBs and parental HOBs were compared.

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