Transcriptomics

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Single-cell transcriptome reveals the reprogramming of immune microenvironment during the transition from MASH to HCC


ABSTRACT: Metabolic dysfunction-associated steatohepatitis (MASH)-driven hepatocellular carcinoma (HCC) development is accompanied by the accumulation of immune cells within the hepatic microenvironment, yet its immunological networks remain obscure. Herein, we illustrate the profound reprogramming of the liver immune microenvironment during the transition from MASH to HCC by single-cell RNA sequencing (scRNA-seq).

ORGANISM(S): Mus musculus

PROVIDER: GSE282630 | GEO | 2025/06/18

REPOSITORIES: GEO

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