Type I Interferon Induced Apoptosis Drives Chronic Wounds in ISG15 deficiency

ABSTRACT: Chronic exposure to IFN-I in ISG15 deficiency drives impaired wound healing, improper macrophage activation and enhanced Epithelial-to-Mesenchymal transition, likely causing fibrosis in multiple organ systems.

ORGANISM(S): Homo sapiens

PROVIDER: GSE283022 | GEO | 2025/11/25

REPOSITORIES: GEO