Transcriptomics

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Pro-cognitive restoration of PV interneuron plasticity in neurodevelopmental disorders


ABSTRACT: To identify candidate regulators of experience-dependent PV IN plasticity genes or “XPGs” in CA3/CA2 PV INs, we designed an in vivo functional screen in adult mice to isolate translated mRNAs from CA3/CA2 PV INs that receive increased mossy fiber inputs, a trigger for experience-dependent PV IN plasticity.

ORGANISM(S): Mus musculus

PROVIDER: GSE283741 | GEO | 2025/07/01

REPOSITORIES: GEO

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