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Integrated transcriptomic and epigenomic profiling of mouse lung cells at the single-cell level

ABSTRACT: Our previous scRNA-seq data suggest that immune and stromal cells exhibit memory properties that contribute to the long-term regulation of lung allergic responses, which are cross-regulated by the co-administration of TLR ligands or bacterial extracts. To further investigate these mechanisms, we performed single-cell multiome sequencing (scMulti-omics) to integrate transcriptomic and epigenomic profiling, focusing on the characterization of immune and stromal cell populations during long-term resolution.

ORGANISM(S): Mus musculus

PROVIDER: GSE284046 | GEO | 2025/12/31

REPOSITORIES: GEO

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