Genomics

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ACGH analysis of familial Alzheimer’s disease with presenilin 2 mutation patient-specific induced pluripotent stem cells


ABSTRACT: We established two clones of induced pluripotent stem cells (iPSC) with the presenilin 2 mutation, N141 (PS2-1 iPSC and PS2-2 iPSC) by retroviral transduction of primary human fibroblasts. To detect the copy number dependent gene expression profiles in primary fibroblast carrying the presenilin 2 mutation N141(before reprogramming) and PS2-1 iPSC and PS2-2 iPSC(after reprogramming), this experiment was designed.

ORGANISM(S): Homo sapiens

PROVIDER: GSE28450 | GEO | 2011/09/10

SECONDARY ACCESSION(S): PRJNA139147

REPOSITORIES: GEO

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