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Transcriptional profiling of calcifying human primary coronary artery smooth muscle cells

ABSTRACT: Transcriptomics analysis of human coronary artery smooth muscle cells cultured in osteogenic medium and PIKfyve inhibition. To study the underlying molecular mechanisms of PIKfyve-mediated vascular calcification, we analyzed the transcriptome of osteogenic medium (OM)-calcified human coronary artery smooth muscle cells that were treated with PIKfyve inhibitors (Apilimod, YM201636) or DMSO control on day 7.

ORGANISM(S): Homo sapiens

PROVIDER: GSE284683 | GEO | 2025/12/31

REPOSITORIES: GEO

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