Transcriptomics

Dataset Information

39

Characterization of differential gene expression in adrenocortical tumors harbouring β-catenin (CTNNB1) mutations.


ABSTRACT: Mutations of β-catenin gene (CTNNB1) are frequent in adrenocortical adenomas (AA) and carcinomas (ACC). However, the target genes of CTNNB1 have not yet been identified in adrenocortical tumors. Our objective was to identify genes de-regulated in adrenocortical tumors harbouring CTNNB1 genetic alterations. Overall design: We compared gene expression profiles of AA with (n: 3) and without (n: 4) CTNNB1 mutations using Affymetrix arrays.

INSTRUMENT(S): [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

ORGANISM(S): Homo sapiens  

SUBMITTER: julien durand  

PROVIDER: GSE28476 | GEO | 2011-04-09

SECONDARY ACCESSION(S): PRJNA139317

REPOSITORIES: GEO

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