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Effect of EDC exposure on differentiation of iPSC derived stem cell islets

ABSTRACT: This project investigates the impact enodcrine disrupting chemicals (EDCs) on differentiation toward stem cell derived islets. RNA sequencing (RNA-seq) was performed on EDCs treated and non-treated islets differentiated from iPSCs to SC-islets. By comparing the transcriptomic profiles of these islets, the study aims to uncover molecular mechanisms affected by EDCs treatment, and the impact on SC-islet fate.

ORGANISM(S): Homo sapiens

PROVIDER: GSE285036 | GEO | 2026/02/11

REPOSITORIES: GEO

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