Genomics

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Reduced TBX5 dosage causes human atrial disease by undermining developmental gene regulation of atrial cardiomyocyte identity [scATAC-seq]


ABSTRACT: In a TBX5-linked human cellular model of atrial disease, we examined the gene networks controlled by TBX5 during human atrial differentiation using single-cell RNA and ATAC sequencing.

ORGANISM(S): Homo sapiens

PROVIDER: GSE285168 | GEO | 2025/12/01

REPOSITORIES: GEO

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