Transcriptomics

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An APE1 Inhibitor Reveals Critical Roles of APE1 Redox Function in Pathogenesis of Chronic Rhinosinusitis and Novel Therapeutics


ABSTRACT: We demonstrated that the Apurinic/apyrimidinic endonuclease 1 (APE1) redox inhibitor, C10, effectively blocked Type 2 inflammation and improved chronic rhinosinusitis (CRS) pathology in a mouse model.

ORGANISM(S): Mus musculus

PROVIDER: GSE285228 | GEO | 2025/07/01

REPOSITORIES: GEO

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