An APE1 Inhibitor Reveals Critical Roles of APE1 Redox Function in Pathogenesis of Chronic Rhinosinusitis and Novel Therapeutics
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ABSTRACT: We demonstrated that the Apurinic/apyrimidinic endonuclease 1 (APE1) redox inhibitor, C10, effectively blocked Type 2 inflammation and improved chronic rhinosinusitis (CRS) pathology in a mouse model.
ORGANISM(S): Mus musculus
PROVIDER: GSE285228 | GEO | 2025/07/01
REPOSITORIES: GEO
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