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Tumor-infiltrating lymphocytes-derived CD8+ clonotypes infiltrate the tumor tissue and mediate tumor regression in glioblastoma [RNA-Seq]

ABSTRACT: IL-2/IL-15/IL-21-expanded TILs achieved complete tumor regression in a hypermutated glioblastoma patient, overcoming the immunosuppressive microenvironment. This case highlights a novel approach for treating gliomas using tailored adoptive cell therapy strategies.

ORGANISM(S): Homo sapiens

PROVIDER: GSE285281 | GEO | 2025/12/02

REPOSITORIES: GEO

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Tumor-infiltrating lymphocytes-derived CD8+ clonotypes infiltrate the tumor tissue and mediate tumor regression in glioblastoma [WES]

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