Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Functional reprogramming of neutrophils within tumors by hypoxia-driven histone lactylation [RNA-seq]

ABSTRACT: We used bulk RNAseq to study the mechanism underlying the functional reprogramming in brain tumors.

ORGANISM(S): Mus musculus

PROVIDER: GSE285509 | GEO | 2025/02/14

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Functional Reprogramming of Neutrophils within the Brain Tumor Microenvironment by Hypoxia-Driven Histone Lactylation.

Project description: Not available

| S-EPMC12133432 | biostudies-literature

Functional reprogramming of neutrophils within tumors by hypoxia-driven histone lactylation [scRNA-seq]

Project description:We used scRNAseq to study the mechanism underlying the functional reprogramming in brain tumors. scRNA-seq of FACS-sorted neutrophils was performed on mice with brain tumors (SB28). We showd that the immunosuppressive ability of brain-tumor infiltrating neutrophils was exclusively mediated by a population of highly glycolytic neutrophils expressing the transferrin receptor CD71.

2025-02-14 | GSE285510 | GEO