Identifying critical lncRNAs in PBMCs linked to sepsis-induced immunosuppression using microarray analysis

ABSTRACT: This study aims to identify key long non-coding RNAs (lncRNAs) and their associated pathways in peripheral blood mononuclear cells (PBMCs) from sepsis immunosuppression patients. Using weighted gene co-expression network analysis (WGCNA), we have constructed a co-expression network to elucidate the molecular mechanisms underlying sepsis-induced immunosuppression. The study utilizes Agilent Human ceRNA Microarray 2019 to profile lncRNA expression in PBMCs from three sepsis patients and three healthy controls.

ORGANISM(S): Homo sapiens

PROVIDER: GSE286082 | GEO | 2025/04/16

REPOSITORIES: GEO