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Transcriptomic analysis of RNA (mRNA/ lncRNA/ circRNA) expression and epitranscriptomic profiling of N4-acetylcytidine-related RNA (mRNA/ lncRNA/ circRNA) acetylation in renal cortex from mice with ischemia reperfusion injury

ABSTRACT: N4-acetylation of cytidine (ac4C) in RNA are crucial for regulating the expression level and promoting the translate efficiency of mRNA. However, epitranscriptomic profiling of ac4C-related RNA (mRNA/ lncRNA/ circRNA) acetylation in renal cortex are largely unknown. Therefore, we profiled the transcriptome-wide ac4C modification in mRNA/ lncRNA/ circRNA in renal cortex from either ischemia reperfusion-acute kidney injury (I/R-AKI) mouse or Sham-operated mouse. At the same time, the expression levels of mRNA/ lncRNA/ circRNA were also evaluated by the sequencing experiment in input group. Therefore, this is an experiment for quantifying both the expression levels and the ac4C modification alterations in mRNA/ lncRNA/ circRNA within renal cortex from I/R-AKI mouse.

ORGANISM(S): Mus musculus

PROVIDER: GSE286507 | GEO | 2026/01/12

REPOSITORIES: GEO

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